
SENSIPAR (Cinacalcet) is a prescription medication used to treat secondary hyperparathyroidism in patients with chronic kidney disease on dialysis and to lower high blood calcium levels in patients with parathyroid carcinoma. It works by increasing the sensitivity of calcium-sensing receptors in the parathyroid glands, leading to a decrease in parathyroid hormone (PTH) levels and associated symptoms.
SENSIPAR acts as a calcimimetic agent, which means it mimics the action of calcium on tissues, particularly the parathyroid glands. By enhancing the sensitivity of these receptors to calcium, SENSIPAR effectively reduces PTH secretion and helps maintain calcium balance in the body.
The dosage of SENSIPAR should be individualized based on serum calcium levels and the clinical response. It is typically taken orally, with or without food. Regular monitoring of serum calcium and PTH levels is essential to ensure effective treatment and adjust the dosage as needed.
Common side effects may include nausea, vomiting, diarrhea, and dizziness. Serious side effects can occur, such as low blood calcium levels (hypocalcemia), which may present with symptoms like muscle spasms, tingling, or seizures. Patients should be advised to report any unusual symptoms to their healthcare provider.
Before starting SENSIPAR, patients should inform their healthcare provider about any existing medical conditions, especially those related to heart problems or low blood calcium. It is also important to discuss any medications currently being taken to avoid potential interactions.
Store SENSIPAR at room temperature away from moisture and heat. Keep out of reach of children and do not use past the expiration date.
Patients should consult their healthcare provider for personalized medical advice, potential drug interactions, and any concerns regarding the use of SENSIPAR.