ELIQUIS

Eliquis (Apixaban) Medicine Description

Drug Class:

Anticoagulant (Direct Factor Xa Inhibitor)

Categories:

• Cardiovascular Medicine
• Antithrombotic Agents

Active Ingredient Name:

Apixaban

Popular and Other Names:

• Brand Name: Eliquis
• Generic Name: Apixaban
• Other Names: Apixabanum (International Nonproprietary Name - INN)

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Mode of Action:

Eliquis (Apixaban) is an anticoagulant medication that inhibits Factor Xa, a crucial enzyme in the blood clotting process. By blocking Factor Xa, Apixaban reduces the formation of blood clots. This action makes it effective in preventing conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke in individuals with atrial fibrillation (AFib).

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How to Use Eliquis:

• Administration: Eliquis is taken orally in tablet form, usually twice daily. The tablets can be taken with or without food.

• Timing: It is essential to take the medication at the same times each day, typically in the morning and evening. Consistency helps maintain effective levels in the bloodstream.

• Missed Dose: If a dose is missed, take it as soon as you remember, unless it is almost time for the next scheduled dose. Do not double the dose to make up for the missed one.

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Recommended Dosage:

1. Stroke Prevention (Atrial Fibrillation):

   • Standard Dosage: 5 mg twice daily.
   • Lower Dosage: In specific cases (e.g., advanced age or low body weight), your doctor may prescribe 2.5 mg twice daily.

2. Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE):

   • Initial Dosage: 10 mg twice daily for 7 days.
   • Maintenance Dosage: 5 mg twice daily after the initial treatment period.

3. Post-Surgery DVT Prevention:

   • Hip Replacement: 2.5 mg twice daily for 35 days.
   • Knee Replacement: 2.5 mg twice daily for 12 days.

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Directions:

1. Consistency:
   Take the medication at regular intervals, ensuring you follow your doctor’s instructions.

2. Swallow Whole:
   Swallow the tablet whole with water. Do not crush or chew.

3. Storage:
   Store Eliquis in a cool, dry place, away from direct sunlight and moisture.

4. Interaction:
   Avoid over-the-counter medications and supplements that increase the risk of bleeding, such as NSAIDs, unless approved by your healthcare provider.

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Cautions:

1. Risk of Bleeding:
   Eliquis increases the risk of bleeding, so avoid activities that could cause injury. Report unusual bleeding or bruising to your doctor immediately.

2. Surgery and Dental Procedures:
   Inform your healthcare provider that you are taking Eliquis before any surgical or dental procedures.

3. Pregnancy and Breastfeeding:
   Consult your doctor before taking Eliquis if you are pregnant, planning to become pregnant, or breastfeeding.

4. Liver and Kidney Issues:
   If you have liver or kidney problems, your doctor may adjust your dosage accordingly.

5. Interaction with Other Medications:
   Eliquis may interact with other anticoagulants, antiplatelet drugs, and certain antidepressants. Discuss your medications with your healthcare provider.

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Manage Side Effects:

1. Common Side Effects:

   • Easy bruising
   • Prolonged bleeding from cuts
   • Nosebleeds
   • Bleeding gums

   Management:
   If these side effects occur, monitor them closely. Contact your healthcare provider if they become more severe or persistent.

2. Serious Side Effects:

   • Severe or uncontrollable bleeding
   • Red, pink, or brown urine
   • Black, tarry stools
   • Coughing up blood or blood clots

   Action:
   If you experience any of these symptoms, seek emergency medical help immediately. In rare cases, Eliquis may cause life-threatening bleeding.

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Guidelines:

1. Follow-Up Monitoring:
   Regular check-ups and blood tests are essential to ensure Eliquis is working effectively and not causing any harmful side effects.

2. Avoid Alcohol:
   Excessive alcohol consumption can increase the risk of bleeding while on Eliquis.

3. Avoid NSAIDs:
   Nonsteroidal anti-inflammatory drugs like ibuprofen should be avoided unless prescribed by your healthcare provider, as they increase the risk of bleeding.

4. Medical Bracelet:
   It is recommended to wear a medical bracelet indicating that you are on Eliquis, especially in emergencies.

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Frequently Asked Questions (FAQs):

1. What is Eliquis used for?
   Eliquis is used to prevent blood clots that could lead to stroke, DVT, or pulmonary embolism, particularly in individuals with atrial fibrillation or those undergoing joint replacement surgery.

2. Can I stop taking Eliquis if I feel better?
   No, stopping Eliquis without your doctor's advice can increase your risk of stroke or blood clots. Always consult your healthcare provider before discontinuing.

3. What should I do if I miss a dose of Eliquis?
   If you miss a dose, take it as soon as possible, unless it is almost time for your next dose. Do not double the dose to make up for the missed one.

4. Can I take Eliquis with aspirin?
   Your doctor may prescribe low-dose aspirin with Eliquis in certain cases. However, high doses of aspirin may increase the risk of bleeding.

5. Can I have surgery while taking Eliquis?
   You may need to stop Eliquis temporarily before surgery to reduce the risk of excessive bleeding. Inform your doctor ahead of time if you need surgery or dental work.

6. Is Eliquis safe during pregnancy?
   The safety of Eliquis during pregnancy has not been well studied. Consult your doctor if you are pregnant or planning to become pregnant while on Eliquis.

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Quick Links:

• Stroke Prevention in Atrial Fibrillation
  Learn more about how Eliquis helps prevent strokes in patients with atrial fibrillation.

• Deep Vein Thrombosis (DVT) Treatment
  Understand how Eliquis is used in the treatment and prevention of DVT.

• Pulmonary Embolism (PE) Management
  Discover how Eliquis helps in managing and preventing life-threatening pulmonary embolism.

• Hip and Knee Surgery Blood Clot Prevention
  See how Eliquis helps prevent blood clots after major hip or knee replacement surgeries.

• Safety and Side Effects
  Find detailed information on the common and serious side effects of Eliquis and how to manage them.